Endocrine Abstracts

Isochromosome Mosaic Turner Syndrome (IMTS) is a variant of Turner Syndrome (TS) characterized by cytogenetic profile of 1 or more additional cell lineages aside from 45,X, and the presence of a structurally abnormal X chromosome consisting of either two short or two long arms. IMTS is rare, with only 8–9% prevalence among women with TS based on international studies, and 15% of all TS in the Philippines. A 20 year old female came in due to amenorrhea and alopecia. Physic...

Background: Polycystic ovary syndrome (PCOS) affects 5–10% of women in the reproductive age group. It is associated with insulin resistance and hyperinsulinemia which is further aggravated during pregnancy. The use of metformin in PCOS is increasingly accepted but its therapeutic use during pregnancy is still a debatable issue. There are few local studies on the use of metformin among PCOS patients and data are lacking among Filipinos.Objectives: To...